C(sp3)-H functionalization of N-protected-dialkylpyrrole derivatives with azodicarboxylates

Chem. Commun., 2025, Accepted Manuscript DOI: 10.1039/D5CC03254G, Communication Jing Guo, Maying Yan, Lei Xiao, Jiajie Li, Douglas W. Stephan, Zheng-wang Qu, Stefan Grimme A metal-free, catalytic route to the activation of C(sp3)-H bonds in N-protected dialkylpyrroles to diazodicarboxylates is reported using HB(C6F5)2 as the optimized catalyst. These reactions tolerate aryl and alkyl substituents...