ChemReactSeek: Artificial Intelligence-Guided Chemical Reaction Protocol Design Using Retrieval-Augmented Large Language Models

Chem. Commun., 2025, Accepted Manuscript DOI: 10.1039/D5CC03155A, Communication Ziyang Gong, Chengwei Zhang, Danyang Song, Weida Xia, Bin Shen, Wei Ke Su, Hongliang Duan, An Su We introduce ChemReactSeek, an advanced artificial intelligence platform that integrates Retrieval-Augmented Generation with Large Language Models (LLMs) to automate the design of chemical reaction protocols. The system employs DeepSeek-v3 to...