Self-Immolative PEGylated Dendritic Drug Conjugates for Cancer Therapy with Enhanced Cellular Uptake

Chem. Commun., 2025, Accepted Manuscript DOI: 10.1039/D5CC02776D, Communication Zining Xia, Yixin Zhang, Xinyi Zuo, Sucan Cheng, Yanwen Tian, Yue Ding A hypoxia-responsive nanomedicine NM-CB/Ce6 with prominent biocompatibility to co-deliver chlorambucil (CB) and chlorin e6 (Ce6) was prepared using a self-immolative PEGylated dendritic drug conjugate block-dendritic-polymer. Upon 650 nm near-infrared light...