Manganese-Mediated C(sp)–Si Cross-Electrophile Coupling of Alkynyl Halides with Chlorosilanes

Chem. Sci., 2025, Accepted Manuscript DOI: 10.1039/D5SC03449C, Edge Article Quan Lin, Liping Lin, Jingjing Wang, Daohong Yu, Zhengwang Chen, Zhong-Xia Wang We present a manganese-mediated cross-electrophile coupling (XEC) that directly constructs C(sp)–Si bonds between alkynyl halides and chlorosilanes. By leveraging manganese as a bifunctional reductant/catalyst, this method enables a mild and...