Employment of a C(sp3)-based nucleophile for photoinduced palladium-catalysed cross-coupling

Chem. Sci., 2025, Advance Article DOI: 10.1039/D5SC02325D, Edge Article Beom Ho Kim, Byeongdo Roh, Dong Jun Kim, Hong Geun Lee This study presents a photoinduced palladium-catalyzed method using sterically demanding unactivated alkyl halide electrophiles and cyclopropanols as a masked nucleophilic counterpart, enabling C(sp3)–C(sp3) cross-coupling under mild conditions.