Amino-Induced Cleavage of Electron-Communicating S-Bridge to Unlock Mixed-Valence Copper for Potent Oxidase-like Catalysis and Selective Sensing

Chem. Sci., 2025, Accepted Manuscript DOI: 10.1039/D5SC03521J, Edge Article Bojin Li, Nan Nan Xia, Chaofeng Huang, Xun Hu, Fei He Transition metal sites with mixed valence often coexisted in diverse catalysis, yet their precise roles remained elusive. Taking a thiadiazole-coordinated Cu nanozyme system for example, we developed ligand side-group engineering...