Chemical-assisted analysis of epigenetic modifications

Chem. Soc. Rev., 2025, Advance Article DOI: 10.1039/D5CS00479A, Review Article Xucong Teng, Qiushuang Zhang, Yicong Dai, Hongwei Hou, Jinghong Li We reviewed chemical-assisted methods for analyzing DNA and RNA modifications from the perspectives of reaction mechanisms, and summarized strategies for distinguishing modified and unmodified bases based on differences in their chemical reactivity.