JAMA | The Latest Medical Research, Reviews, and Guidelines Follow Alteplase for Acute Ischemic Stroke at 4.5 to 24 Hours This randomized clinical trial examines the safety and efficacy of intravenous alteplase administered 4.5 to 24 hours after stroke onset in patients with salvageable brain tissue. https://jamanetwork.com/journals/jama/fullarticle/2837438 jamanetwork.com
