An interfacial-intramolecular electron highway for accelerated electrocatalytic CO2 reduction by an O2-tolerant formate dehydrogenase

Formate dehydrogenases (FDH) offer a route for carbon fixation but are limited by interfacial-intramolecular electron transfer (IIET) and oxygen sensitivity. Here the authors mine an FDH from S. oneidensis MR-1 featuring oxygen compatibility and direct-electron-transfer electrocatalytic performances.