Nature | Communications
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APOE ε4 carriership status enhances age-related changes in Alzheimer’s disease plasma biomarkers concentrations
In cognitively normal individuals, the rate of change in concentrations of plasma ptau217 and Aβ−42/40 over age differs between APOE ε4 carriers and non-carriers. For p-tau217, the effect of APOE ε4 carriership is stronger in males than females.