Physical Review Letters
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Cell Stiffness-Mediated Mechanochemical Waves in Three-Dimensional Tissues
Author(s): Pengyu Yu, Rui Zhang, and Bo Li
Tissue development, physiological or pathological, commonly involves stiffness alterations in the constituent cells. Here, we develop a three-dimensional (3D) active vertex model incorporating mechanical feedback from extracellular signal-regulated kinase (ERK) to explore mechanochemical waves in ti… [Phys. Rev. Lett. 135, 108401] Published Tue Sep 02, 2025