Scientific American Content | Global Follow Deep-Sea Worm Produces Orpiment, a Toxic Yellow Pigment Used in Historical Art A deep-sea worm that lives in hydrothermal vents is the first known animal to create orpiment, a toxic, arsenic-containing mineral that was used by artists for centuries https://www.scientificamerican.com/article/deep-sea-worm-produces-orpiment-a-toxic-yellow-pigment-used-in-historical/ scientificamerican.com