Enzyme inhibition-enabled CRISPR/Cas12a biosensing system for heparin-related non-nucleic acid biomarkers

Chem. Commun., 2025, Accepted Manuscript DOI: 10.1039/D5CC03376D, Communication Ruo Ma, Wenjiao Fan, Yueran Wang, Xinrui Fei, Chenghui Liu Different from conventional CRISPR/Cas12a systems that must employ sophisticated functional nucleic acids, protein switch or allosteric transcription factors (aTFs)-based signal conversion for non-nucleic acid analysis, this work realizes more facile...