Evolutionarily reinforced GC-rich motif enables non-AUG translation in mammals under eIF1/5MP-mediated fidelity control | Science Advances
Non-AUG translation contributes to proteome diversity, but its regulatory principles remain unclear. Here, we show that a GCC-rich upstream extension, termed the NAT1 motif, acts as a potent enhancer of near-cognate initiation in mammals. Cell-free and ...
