Physical Review Letters
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Fitness-Driven Scaling Laws between mRNA and Protein Levels
Author(s): Yichen Yan (颜逸辰) and Jie Lin (林杰)
The relationship between protein and messenger RNA (mRNA) levels is a key aspect of gene expression. Although a strong mRNA-protein correlation is widely observed, the evolutionary force driving the correlation remains poorly understood, undermining the reliability of using mRNA abundance as a proxy… [Phys. Rev. Lett. 137, 048402] Published Wed Jul 22, 2026