The science of aging, geroscience, translates to its medical application, or geromedicine. This transition will be facilitated by systematic omics technologies quantifying pro-aging (gerogenic) and anti-aging (gerosuppressive) molecules in biological samples. If deconvoluted in a appropriate fashion, this information will help to personalize specific treatments for the prevention, interception, and treatment of age-related diseases as well as for the optimization of health and fitness.