Science Magazine | AAAS: Science Advances Follow HnRNP C binding to inverted Alu elements protects the transcriptome from pre-mRNA circularization | Science Advances HnRNP C is a general repressor of circular RNA (circRNA) biogenesis in group 3 medulloblastoma cells. https://www.science.org/doi/10.1126/sciadv.aea2351 science.org