Ligand-tuned extracellular domain dynamics are correlated with signaling states in an adhesion GPCR | Science Advances
Adhesion G protein–coupled receptors (aGPCRs) transduce signals via engagement of their large extracellular regions (ECRs) with adhesion partners. ADGRG6 (GPR126) is an aGPCR vital for the development of multiple organs and myelination. ECR ...