Liquid-repellent particle coating enables near-frictionless motion of pico- to nanoliter droplets

The precise control of tiny droplets on surfaces is essential for advanced manufacturing, pharmaceuticals, and next‐generation lab‐on‐a‐chip diagnostics. However, once droplet volume reaches pico- and nanoliter scales, the droplets become extremely sensitive to microscopic surface irregularities, and friction at the solid‐liquid interface becomes a major obstacle to smooth transport.