JAMA | The Latest Medical Research, Reviews, and Guidelines Follow Nalbuphine for Cough Caused by Idiopathic Pulmonary Fibrosis To the Editor In the CORAL randomized clinical trial of nalbuphine ER in IPF, nalbuphine appeared to be a highly effective therapy in individuals experiencing chronic cough. https://jamanetwork.com/journals/jama/fullarticle/2849514 jamanetwork.com