NANOG Assembles into Self-Limi... Note

NANOG Assembles into Self-Limiting Aging Micelles That Drive a Sol-Gel Transition and Modulate DNA Dynamics

Author(s): Amandine Hong-Minh, Yair Augusto Gutiérrez Fosado, Abbie Guild, Nicholas Mullin, Laura Spagnolo, Ian Chambers, and Davide Michieletto Proteins and nucleic acids form non-Newtonian liquids with complex rheological properties that contribute to their function in vivo. Here, we investigate the rheology of the transcription factor NANOG, a key protein to maintain embryonic stem cell pluripotency. We find that, at high concentrations, … [Phys. Rev. Lett. 137, 018402] Published Tue Jun 30, 2026