Author(s): Tomas André, Alfredo Bellisario, Wilma Kraft, Nicuşor Tîmneanu, and Carl Caleman We solve the orientation recovery of a tumbling protein in the gas phase from single-event measurements of the spatial positions of its ions after an x-ray laser-induced explosion. We simulate diffracted x-ray signal and ion dynamics under experimental conditions and compare our method to convention… [Phys. Rev. Lett. 137, 128401] Published Mon Sep 14, 2026