Gizmodo Follow People Can Lose Their Zest for Life After Starting GLP-1s, Docs Warn A new case report highlights the potential risk of "anhedonia" from high doses of tirzepatide, though it can be treated effectively. https://gizmodo.com/people-can-lose-their-zest-for-life-after-starting-glp-1s-docs-warn-2000786586 gizmodo.com