Author(s): Alessandra Lucchetti, Lukas H. Kristensen, Mogens H. Jensen, and Mathias S. Heltberg Oscillations constitute a defining feature of nonequilibrium processes of life. We analyze a minimal degradation-mediated negative feedback loop, in which the final species in a linear cascade enzymatically degrades the first component. By coupling mean-field ordinary differential equations with a p… [Phys. Rev. Lett. 137, 048401] Published Wed Jul 22, 2026