Preparation of nucleoside analogues: opportunities for innovation at the interface of synthetic chemistry and biocatalysis

Chem. Sci., 2025, Accepted Manuscript DOI: 10.1039/D5SC03026A, Perspective Admir Salihovic, Andrea Taladriz-Sender, Glenn A Burley Nucleoside analogues are used throughout nature. They comprise the key building blocks in nucleic acids and in second messenger small molecules. Additionally, modifications to the sugar and nucleobase moieties have...