Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01399B, Review Article Zijing Suo, Yuyao Sun, Jianping Lai, Lei Wang Paradigm shifts and pathways for high-loading electrocatalytic electrodes from static design to dynamic intelligent systems.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS90053D, Editorial We would like to take this opportunity to highlight the Outstanding Reviewers for Chemical Society Reviews in 2025, as selected by the editorial team for their significant contribution to the journal.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00145A, Review Article Eito Moriya, Junichiro Yamaguchi Functional group translocation directly relocates functional groups without changing the molecular scaffold, enabling access to positional isomers. This review outlines the concept and advances in aromatic and aliphatic systems.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01539A, Tutorial Review José Justicia, Sara P. Morcillo Control over radical generation governs β-scission and enables selective skeletal editing.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00036C, Review Article Shaoqing Guan, Qingbin Li, Can Gao, Huanli Dong This review focuses on ambipolar organic light-emitting transistors (OLETs), emphasizing the rational design and synthesis of ambipolar high-mobility emissive semiconductors as well as device structure optimization.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01074H, Review Article Muqing Si, Weihao Feng, Tao Chen, Wei Lu This review highlights how coordination-crosslinked polymer networks translate dynamic metal–ligand coordination bonds and their synergy with other dynamic bonds into responsive soft materials.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00242K, Review Article Zhuo-Qi Shi, Liang Ding, Ze-Cheng Yao, Tang Tang, Rui Cao, Jin-Song Hu This review highlights the multiscale cathode design for high-temperature proton exchange membrane fuel cells, bridging the gap from atomic-level catalyst design and interfacial engineering to device-level catalyst layer optimization.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01136A, Review Article Qiyue Wang, Hui Du, Xinting Li, Xinke Hu, Nayeon Kang, Heemin Kang, Fangyuan Li, Daishun Ling This review highlights recent advances in dynamic self-assembled cuproptosis nanosystems that leverage copper coordination chemistry and stimuli-responsive structural reconfiguration for spatiotemporally controlled cancer therapy and imaging.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00154H, Review Article Mengjie Hao, Xiaolu Liu, Yinghui Xie, Hanzhi Chen, He Gu, Chuanlei Luo, Muliang Xiao, Xinyue Zhang, Jiaqi Li, Xinyi Yang, Juyao Zhang, Hui Yang, Fuyou Fan, Juncheng Liang, Xiangke Wang This review comprehensively summarizes and discusses recent advances in framework materials for nuclear waste treatment, covering key aspects of materials design, synthesis, performance, and fundamental structure–property–function relationships.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01317H, Review Article Zhaoze Shen, Qian Wang, Kequan Cao, Xuerong Song, Binbin Yu, Jiajia Ning, Fei Huang, Jianjun Tian This review elucidates advances in eco-friendly Zn chalcogenide nanocrystals, detailing growth mechanisms, controllable synthesis, and optoelectronic applications, and proposes remaining challenges alongside future perspectives.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01554E, Review Article Biyun Ren, He Dong, Junjie Sun, Chenxin Ran, Yingdong Xia, Lingfeng Chao, Yonghua Chen, Wei Huang This review highlights recent advances in highly efficient and stable inverted PSCs and discusses key directions for achieving large-area fabrication and enhanced stability to accelerate commercialization.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00363J, Tutorial Review Hanle Liu, Shunhan Jia, Ruhan Wang, Limin Wu, Xiaofu Sun, Buxing Han Three interaction models are introduced to help analyse intermediate behaviour and reaction pathways at key reaction steps.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00501B, Review Article AJing Song, Yuanyuan Ma, Ziyang Wu, Min Kuang, Yuqin Zou, Jianping Yang Electrocatalysis provides a sustainable route for polymer monomer synthesis from renewable feedstocks, and this review summarizes three representative strategies together with system-level considerations for scalable implementation.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS00007F, Review Article Chang-Hee Lee, Joo Hee Choi, Eunseo Lee, Na Ryeong Kim, Ji Young Hyun, Hak Joong Kim, Injae Shin We highlight recent advances in cell-surface glycan engineering and its applications for studying glycan-mediated biological events and developing therapeutics.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D4CS01250J, Review Article Yu Zhan, Nan Chen, Li Li, Feng Wu, Renjie Chen This review provides a comprehensive overview of the recent advances in the artificial intelligence–assisted design of high-voltage electrolytes, introduces the AI4B paradigm, and outlines the key directions for future research.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00165C, Review Article Dmytro Kobzev, Olesia Kulyk, Roman A. Barmin, Anatoliy Tatarets, Roger M. Pallares, Fabian Kiessling, Twan Lammers, Quim Peña We present a large-scale scientometric (pre-)clinical landscape analysis of stimuli-responsive therapeutics, highlighting the impact of nano-/micro-scale material platforms, and mapping translational barriers and strategies to overcome them.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00331A, Review Article Jean Pinson Photografting enables the covalent modification of a wide variety of surfaces—including polymers, metals, carbons, and oxides—through irradiation of a deposited solution.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01298H, Tutorial Review Zhangkai Cui, Hongjian Lu This review presents a unified, bond-centric framework for direct deaminative functionalization, redefining amines as versatile handles for step-economic C–C and C–heteroatom bond construction.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00071A, Review Article Priyanka Dey, Nick Stone, Pavel Matousek Spatially offset Raman spectroscopy (SORS) and its surface-enhanced variant, SESORS, have emerged as transformative techniques in analytical chemistry and biomedical diagnostics, enabling non-invasive, depth-resolved molecular sensing.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00515B, Review Article Yixiao Huang, Jianguo Tang, Zhengquan Li, Dongling Ma, Jin Wang, Zhonglin Du Eco-friendly indium-based quantum dots (InQDs) provide a new direction for designing novel sustainable heavy-metal-free photocatalysts.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS00239G, Review Article Junxian Liu, Ting Liao, Zhongfang Chen, Liangzhi Kou Spin polarization offers a powerful lever for catalysis by tuning d-band levels, eg occupancy, carrier separation, and spin filtering, enabling advances in HER, OER, ORR, CO2RR, ammonia synthesis, and CO oxidation.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00157B, Tutorial Review Rasmus Ringström, S. Rasoul Hashemi, Yuanxin Liang, Nicholas J. Hestand, Karl Börjesson This review presents a practical toolbox for modelling exciton coupling in molecular aggregates, from Coulombic interactions and vibronic coupling to charge-transfer effects.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01292A, Tutorial Review Linbo Jiang, Shichun Mu This review investigates intelligent self-optimization effects, responsive mechanisms and multimodal intelligent catalysis, associated challenges and solutions, aiming to promote on-demand applications in complex multi-scenario environments.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00079G, Review Article Joonyoung F. Joung, Nicholas Casetti, Priyanka Raghavan, Connor W. Coley Reaction outcome prediction can be formulated in multiple ways, spanning physics-based exploration of reaction pathways and data-driven prediction of product likelihoods.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS00925A, Tutorial Review Rebeka Rita Reszegi, Wenyao Zhen, Xiaoyuan Chen, Jingjing Zhang This tutorial review outlines design principles for switchable and biodegradable nanostructures in cancer imaging, with emphasis on activation, stability, and clearance.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS90041K, Correction Natalia Yantara, Xuechao Xing, Divyam Sharma, Darrell Jun Jie Tay, Shibi Varku, Nripan Mathews

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D4CS00071D, Review Article Francesco Carraro, Miriam de J. Velásquez-Hernández, Anita Emmerstorfer-Augustin, Daniel Kracher, Qilu Wu, Robert Kourist, Lien-Yang Chou, Ju Ge, Fa-Kuen Shieh, Christian Doonan, Paolo Falcaro This review summarizes recent advances in cells@MOFs, cells@COFs, and cells@HOFs: synthesis strategies, cell–framework interactions, viability assessment, and advanced biotechnological applications.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01295C, Tutorial Review Eunji Kim, Min-Goo Lee, Yoonji Heo, Sumin Kim, Jiwoo Seo, Sungwook Jung, Jong Seung Kim, Min Kim Covalent organic frameworks (COFs), with their customizable structures and properties, can be employed as comprehensive platforms to induce ferroptosis and pyroptosis.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS00526D, Review Article Yongzhi Chen, Zhihao Zhang, Donglin Jiang This review maps strategies to achieve single crystal COFs, outlining methodological developments toward precise crystallization control and linking structure integrity with enhanced properties and advanced functional applications.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS90040B, Correction Shengqiang Liu, Leipeng Li, Bing Chen, Quanlin Liu, Feng Wang

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00465B, Review Article Ke Jiang, Zhining Yuan, Ling Zhang, Banglin Chen, Guodong Qian Pore engineering bridges MOF chemistry and HOF mechanics, enabling chemically and mechanically gated crystalline frameworks for precision drug delivery.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01387A, Review Article Douglas B. Kell, Ivayla Roberts Rugged protein fitness landscapes can be learned from sparse sequence–activity data. Machine learning plus extreme-value theory can guide directed evolution toward rarer, higher-activity variants.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00132G, Tutorial Review Yi Wei, Huimin Kang, Yuxuan Wang, Yulian Liu, Zewei Quan Chiral hybrid metal halides are promising circularly polarized luminescence materials with high emission efficiency and large dissymmetry factor. This review summarizes CPL generation, amplification strategies, and emerging applications.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00318D, Tutorial Review Juncheng Zhu, Zijia Lin, Yang Wu, Yongfu Sun, Yi Xie This review categorizes modification strategies into surface and interface atomic engineering and systematically elucidates their impacts on electronic structures and photocatalytic performances.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00220J, Tutorial Review Xinyu Chen, Yuanhuan Qiu, Jin-Jiang Zhang, Xiangyang Liu, Ji Ma, Xu Wang, Xinliang Feng Recent advances in bottom-up synthesis strategies have enabled precise control over the edge, backbone, and heterostructure of graphene nanoribbons.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01422K, Review Article Jiahong Li, Jin Qu, Wei Gao A mechanism-driven framework for tissue–bioelectronics interfaces, integrating interfacial mechanisms, materials, structural design and fabrication to enable stable, conformal bioelectronic systems for continuous monitoring and therapy.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS00068A, Review Article Jun-Jie Chen, Shu-Sheng Chen, Qiu-Zhu Wang, Huan-Ming Huang This review highlights recent advances in photochemical rearrangements involving diradical intermediates, including ring expansion, ring contraction, ring construction, applications in natural products and materials synthesis.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01412C, Review Article Xinglong Chen, Cong Hu, Heejeong Kim, Lemeng Zhang, Zhipengjun Zhang, Hongwen Liu, Juyoung Yoon Optical probes and their applications in biomedicine.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01323B, Review Article Yihan Chen, Yuanqing Ding, Han Lin, Jianlin Shi Stimuli-responsive nanoplatforms integrate endogenous cues and external fields to enable BBB-crossing delivery, neuromodulation and imaging-guided therapy, advancing adaptive treatment for CNS disorders.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS00047E, Review Article Daeyeon Won, Jiyong Ahn, Jooyeun Chong, Ahyoung Cho, Taehyun Kim, Seok Hwan Choi, Deog-Gyu Seo, Jiheong Kang, Seung Hwan Ko In this review, we introduce the latest discoveries in the interaction of lasers with various functional polymers, discussing energy delivery mechanisms and their influence on structure modifications and property changes.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS00823A, Review Article Xueqian Chen, Xuejie Li, Richard D. Tilley, J. Justin Gooding This review covers interfacial design of nanoparticle modification, including the impact of the biomolecule orientation and coverage, the composition of surface modifying layers and spatial distribution of biomolecules on nanoparticles.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D6CS90039A, Correction Juan José Patiño López, Kelly G. Rivera Botia, Kevin Ballestas, Esteban Velilla, Juan Felipe Montoya, Franklin Jaramillo, Daniel Ramirez

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01408E, Review Article Thaynan A. B. Chagas, Manoel T. Rodrigues, Fábio S. Fernandes, Luna S. dos Santos, Cíntia D. F. Milagre, Wanda P. Almeida, Fernando Coelho The MBH reaction is a chemical transformation that offers several sustainability advantages and enables the synthesis of small, polyfunctionalised products with high synthetic versatility. In this review, we discuss some of these sustainable aspects.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D4CS00445K, Review Article Fengrui Yang, Zhe Li, Lingling Lei, Ying Zhou, Xiaobing Zhang, Guosheng Song This Review systematically summarizes organic activatable afterglow probes, covering their material categories, luminescence mechanisms, responsive design strategies, performance optimization approaches, and representative biological applications.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS00384A, Review Article Fu-Jia Song, Pingru Su, Xue Li, Chun-Hua Yan, Jun-Long Zhang, Yu Tang Harnessing RE coordination chemistry, antenna effects, and ligand engineering, this review establishes ligand–RE3+ structure–property correlations, outlines photofunctional strategies, and bridges fundamentals to emerging technologies.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01312G, Review Article Wei-Yang Li, Rakesh Kumar Gupta, Kun Zhou, Yan-Feng Bi, Sukhendu Mandal, Di Sun Summary of design strategies and synthesis methods of atomically precise metal nanoclusters for photothermal conversion, exemplified by various representative systems.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS00509D, Review Article Liang Zhang, Yuechun Li, Yuanyuan Zhao, Sheng Chen, Jing Ke, Iman Zarei, Hao Song, Chengzhong Yu, Lizhi Liu Hollow micro-/nanostructures enable bacterial biosensing and antibacterial therapy, addressing scalability and clinical translation for post-antibiotic era.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01327E, Review Article Hangwei Jia, Bailin Chen, Fangfang Zhang, Xueling Hou, Shilie Pan π-CUCP provides a new direction for designing novel high-performance optical crystals.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01092F, Review Article Yue Liu, Qing-Yu Zhao, Si-Dan Guo, Kang Cai Synthetic receptors for steroids have progressed from fundamental molecular recognition to diverse biomedical applications. This review summarizes recent advances and highlights their roles in sensing, imaging, and therapeutic contexts.

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS01279A, Review Article Qiang Zhu, Antonio Fernandez This review provides an overview of hydrogen-bonded organic frameworks nanomaterials, focusing on classification, fabrication strategies, diverse applications, and future perspectives in this evolving field.