SherlockChain is a security analysis framework combining Slither's capabilities with AI features for detecting vulnerabilities in Solidity, Vyper, and Plutus smart contracts. It offers comprehensive vulnerability detection, prioritizing high-impact issues like reentrancy and unprotected upgrades. AI-powered analysis enhances accuracy and precision, providing actionable insights. SherlockChain seamlessly integrates with popular development frameworks like Hardhat, Foundry, and Brownie. Its intuitive reporting simplifies understanding and addressing identified issues. The framework's flexibility allows for customizable analyses and detectors. Continuous monitoring through CI/CD integration ensures ongoing security. AI integration brings intelligent vulnerability prioritization, automated remediation suggestions, and proactive security auditing. Users can interact with SherlockChain using natural language for queries and detailed responses. The --help command provides comprehensive usage information, including options for vulnerability detection, reporting, filtering, AI integration, and integration with development frameworks. The AI-Powered Detectors table lists the detectors, their purpose, impact, and confidence levels.