Supply chain security is a broader challenge that encompasses the entire journey from code creation to production deployment, including source security, build security, artifact security, deployment security, and tool security. A weakness anywhere in the chain can compromise the entire software delivery process. The 2020 SolarWinds attack illustrates the devastating impact of a supply chain attack, where state-sponsored attackers compromised the build pipeline of SolarWinds' Orion network management software. Many organizations remain exposed to supply chain threats due to common misconceptions, such as thinking software supply chain security equals dependency scanning or focusing only on open source components. Artificial intelligence (AI) is introducing new attack vectors and amplifying existing ones, reshaping the entire development lifecycle and introducing significant security blind spots. Organizations struggle to act effectively due to four critical barriers: the false economy mindset, skills shortage reality, misaligned organizational incentives, and tool complexity overload. Supply chain attacks create risk and expenses that extend far beyond initial remediation, including time, reputation damage, regulatory reality, and operational disruption. Current approaches often confuse security activity with security impact, deploying scanners and generating lengthy reports that create more problems than they solve. To succeed, organizations must fundamentally rethink how security integrates with development workflows and review end-to-end software delivery workflows to simplify processes, reduce tools, and improve collaboration. Integrated DevSecOps platforms can address these challenges by bringing security directly into the development workflow.