Physical Review Letters
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State- versus Reaction-Based Information Processing in Biochemical Networks
Author(s): Anne-Lena Moor, Age Tjalma, Manuel Reinhardt, Pieter Rein ten Wolde, and Christoph Zechner
Trajectory mutual information is frequently used to quantify information transfer in biochemical systems. Tractable solutions of the trajectory mutual information can be obtained via the widely used linear-noise approximation (LNA) using Gaussian channel theory. This approach is expected to be accur… [Phys. Rev. Lett. 136, 248401] Published Wed Jun 17, 2026