암세포는 세포독성 T세포를 억제하기 위해 헤지호그 경로를 활성화함으로써 UPR 인자 CREB3L2를 분비한다.
science.org
Noncanonical UPR factor CREB3L2 drives immune evasion of triple-negative breast cancer through Hedgehog pathway modulation in T cells | Science Advances
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