A cocktail of Cu2+- and Zn2+-peptoid-based chelators can stop ROS formation for Alzheimer's disease therapy

Chem. Sci., 2024, Advance Article DOI: 10.1039/D4SC04313H, Edge Article Anastasia E. Behar, Galia Maayan The formation of reactive oxygen species (ROS) in the brain can cause neuropathologic degradation associated with Alzheimer's Disease (AD). We report on a cocktail of two chelators that target Cu and Zn and effectively inhibit ROS formation.