A simple protocol for stereoselective construction of novel β-sulfanyl vinyl sulfonyl fluorides

Chem. Commun., 2025, Advance Article DOI: 10.1039/D5CC00029G, Communication Monday Peter Ajisafe, Heba H. Mohamedy, Eman Fayad, Fayez Althobaiti, Hanadi A. Katouah, Hua-Li Qin The addition of thiols to 2-bromoprop-2-ene-1-sulfonyl fluoride (BPESF) in the presence of an organic base has been successfully employed for the synthesis of highly functionalized sulfanyl vinyl sulfonyl fluorides with 100% stereoselectivity.