Chem. Commun., 2025, Accepted Manuscript DOI: 10.1039/D5CC04336K, Highlight Ranran Cui, Hui Teng, Xuan Huang, Junmin Zhang Deuterated compounds possess significant research value. As interest in chiral deuterated compounds intensifies, various deuteration methods are garnering increased attention. This article primarily reviews the asymmetric deuterium synthesis methods reported...