Catalyst-free efficient synthesis of functionalized 1,2,4-triazole via ring opening/cyclization of arylidene thiazolone with aryl/alkyl-hydrazine

Chem. Commun., 2025, Accepted Manuscript DOI: 10.1039/D5CC02145F, Communication Akanksha Kumari, Anshul Jain, Himani Sharma, Sermadurai Selvakumar, Nirmal K. Rana We report a catalyst-free synthesis of hydrazone-substituted 1,2,4-triazoles via ring opening/intramolecular cyclization of arylidene thiazolone by aryl/alkyl-hydrazine. The reaction exhibits a broad substrate scope and is demonstrated on a gram...