Chemical proteomics-based identification of artesunate as a POLH-PHB1 interaction disruptor

Chem. Commun., 2026, Accepted Manuscript DOI: 10.1039/D5CC06580A, Communication Donghui Ma, Jiawen Li, qiao He, Xiaoxia Dai, Changjun You A chemical proteomics approach was employed to quantitatively profile the changes in the POLH interactome upon artesunate treatment in HEK293T human embryonic kidney cells. The results demonstrated the inhibitory effect...