Framework for De novo Sequencing of Peptide Mixtures via Network Analysis and Two-Dimensional Tandem Mass Spectrometry
Chem. Sci., 2025, Accepted Manuscript DOI: 10.1039/D5SC03762J, Edge Article
MyPhuong T. Le, Yu Zhu, Eric Thomas Dziekonski, Dylan T. Holden, David F. Gleich, R. Graham Cooks Two-dimensional tandem mass spectrometry (2D MS/MS) provides in-depth biopolymer structural information previously not directly accessible with traditional one-dimensional MS/MS workflows, and in significantly less time (<1 second per sample). In...