Ir(III)-Catalyzed Selective C-H Acylmethylation and Dicarbonylation of Indolizines with β-Ketosulfoxonium Ylides
Chem. Commun., 2025, Accepted Manuscript DOI: 10.1039/D5CC04380H, Communication
Shang-Shi Zhang, Zi-Feng Yang, Yuan-Jie Meng, Xin-Xing Liu, Jiaohang Wei, Wen-Rong Wu, Xiang Liu, Pengju Feng Herein, we report an Ir(III)-catalyzed regioselective C-H acylmethylation of indolizines with β-ketosulfoxonium ylides, enabling the efficient synthesis of C3-functionalized indolizine derivatives. By modifying the reaction conditions, a controllable Ir(III)-catalyzed dicarbonylation...
