Chem. Sci., 2026, Accepted Manuscript DOI: 10.1039/D6SC02576E, Edge Article Zhengnuo Ba, Jiadong Tang, Junji Zhang, Chen Wang Palladium nanoclusters (Pd NCs) represent a promising candidate for intracellular redox catalysis owing to their capacity to generate reactive oxygen species (ROS). Yet, in living systems, their catalytic performance is...