Metal free [3+2] cycloadditions of alkylidene cyclopropanes via a non-classical “bow-tie” cation
Chem. Sci., 2026, Accepted Manuscript DOI: 10.1039/D5SC09989G, Edge Article
Anthony Izzotti, Vanessa S. Watts, Philip Karageorghis, James L Gleason Abstract: Treatment of cyclopropylidene-containing 1,5-hexadienes with either diazepane carboxylate organocatalysts or Lewis acids initiates a tandem Michael addition – cyclopropane ring-opening (MACRO) sequence resulting in the formation of [3.2.1]-bridged bicycles....
