Nucleic acid nanotechnology in tumor microenvironment research: from illumination to intervention for enhanced immunotherapy

Chem. Soc. Rev., 2026, Advance Article DOI: 10.1039/D5CS00602C, Review Article Jiayi Lu, Wei Zhai, Min Li, Xiaolei Zuo, Junhua Zheng, Shaopeng Wang Nucleic acid nanotechnology provides powerful approaches for non-invasive biomarker imaging and immune modulation, offering new opportunities to illuminate and therapeutically intervene in the tumor microenvironment.