Several years ago, Amy Pearl developed a mysterious allergy to meat after consuming it for decades without issue. This allergy was linked to a sugar called Alpha Gal, transmitted by the bite of a lone star tick. Amy's story highlighted a broader problem that extends beyond dietary restrictions. A recent update explores the implications of Alpha Gal for medical advancements, specifically pig-to-human organ transplants. The report visits NYU Langone Health to witness a groundbreaking kidney transplant from a genetically modified pig. It also features insights from Revivicor, the company responsible for breeding the pig. The piece revisits Amy to gauge her perspective on this evolving medical landscape. The original story was reported by Latif Nasser and produced by Annie McEwen and Matt Kielty. This update was reported and produced by Sarah Qari. Support for Radiolab comes from listener donations and memberships.