Splicing-associated network PAK1-CLK1/4-SRRM1 is a vulnerability to overcome chemoresistance in huma

Splicing-associated network PAK1-CLK1/4-SRRM1 is a vulnerability to overcome chemoresistance in human and mouse acute myeloid leukemia | Science Translational Medicine

Chemoresistance in acute myeloid leukemia depends on an active PAK1-CLK1/4-SRRM1 splicing network that can be targeted to prevent relapse.