Stapled histone H3 tails are super-substrates for lysine methyltransferase SETD7

Chem. Sci., 2025, Accepted Manuscript DOI: 10.1039/D5SC08094K, Edge Article Nurgül Bilgin, Laust Moesgaard, Jacob Kongsted, Jasmin Mecinović The SETD7-catalysed methylation of lysine 4 in histone 3 (H3K4) plays an important role in the epigenetic control of eukaryotic gene expression. The N-terminal tail of histone H3 binds to...