Chem. Commun., 2025, Advance Article DOI: 10.1039/D5CC02925B, Feature Article Malefo Tshepiso Mofokeng, Onyisi Christiana Didamson, Heidi Abrahamse Cancer stem cells have emerged as an interesting field in oncology due to their metastatic and resistance potential to chemotherapy and radiation therapy, resulting in the resurfacing of cancer even after multiple treatment attempts.