The synthesis of [18F]SynVesT-1 and [18F]SynVesT-2 from enantioenriched boronic esters
Chem. Commun., 2025, Accepted Manuscript DOI: 10.1039/D5CC05507E, Communication
Marong Qin, Pawan Mishra, Jasmine Hind, Ian Fallis, Matthew Tredwell Enantioenrcihed [18F]SynVesT-1 and [18F]SynVesT-2 are prepared from the corresponding enantioenriched arylboronic esters and [18F]fluoride mediated by (Py)4Cu(OTf)2. The 18F-reaction is optimised on an automated synthesiser to produce multi-GBq quantites of...