Visible-Light-Promoted Synthesis of Imidazo[1,5-a]indole-3-ones via Cascade Carbene N–H Insertion and Oxidative Cyclization
Chem. Commun., 2025, Accepted Manuscript DOI: 10.1039/D5CC05725F, Communication
Shou-Yang Tang, Qian-Qian Sang, Ze-Le Chen, Bao-Gui Cai, Jun Xuan A visible-light-induced, transition-metal-free cascade reaction of indole-1-carboxamides with aryl diazoacetates has been developed, providing efficient access to imidazo[1,5-a]indole-3-ones. The transformation proceeds via sequential carbene N–H insertion, base-promoted intramolecular cyclization, and...