Cryptic splicing in synaptic and membrane excitability genes links TDP-43 loss to neuronal dysfunction | Science Translational Medicine science.org
Neutralizing antibodies elicited in nonhuman primates by an enterovirus D68 virus-like particle vaccine target receptor binding sites | Science Translational Medicine science.org
HIV-1 infection converts CD4+ T cells to HLA class II–restricted CD8+ T cells | Science Translational Medicine science.org
Claudin-1 targeting suppresses tumor growth, invasion, and metastasis in patient-derived cholangiocarcinoma models | Science Translational Medicine science.org
Toll-like receptor 5 protects against murine lung fibrosis through reduced dysbiosis, and TLR5 deficiency is associated with human IPF | Science Translational Medicine science.org
Genomic instability drives POSTN+ myofibroblasts via STING-WNT axis to promote immunosuppression and PARPi resistance in ovarian cancer | Science Translational Medicine science.org
Coordinated regulation using small-molecule drugs enables controlled therapeutic genome editing and enhanced genomic precision in situ | Science Translational Medicine science.org
Treatment of Shiga toxin–producing E. coli infection by CRISPR-Cas–targeted cleavage of the Shiga toxin gene in animal models | Science Translational Medicine science.org
CCR5 and CD74 are potential therapeutic targets for necroinflammation in preclinical cholesterol crystal embolism | Science Translational Medicine science.org
